BioMed Research International / 2014 / Article / Fig 3

Research Article

Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model

Figure 3

Transplantation of MSCs-BDNF improved functional outcome after ischemia. (a) The MSCs and MSCs-BDNF groups exhibited better sensorimotor function compared with the PBS group ( , each group). The MSCs-BDNF group exhibited the fastest recovery compared with the other groups ( ). (b) The MSCs-BDNF group had better running function compared with the other groups at 28 days after MCAO (* ). (c) Brain slices were stained with TTC to visualize lesions ( , each group). (d) 14 days after MCAO, significant differences of %CIV were detected in each group (* and ** ).

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