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BioMed Research International
Volume 2014 (2014), Article ID 132369, 7 pages
Research Article

Evaluation of Pain Regression in Patients with Temporomandibular Dysfunction Treated by Intra-Articular Platelet-Rich Plasma Injections: A Preliminary Report

1Department of Dental Prosthetics, Consulting Room of Temporomandibular Joint Dysfunctions, Jagiellonian University, Medical College, 4 Montelupich Street, 31-155 Krakow, Poland
2Department of Cranio-Maxillofacial, Oncological and Reconstructive Surgery, Jagiellonian University, Medical College, 1 Zlotej Jesieni Street, 31-826 Krakow, Poland
3Department of Dental Surgery, Wroclaw Medical University, 26 Krakowska Street, 50-425 Wroclaw, Poland

Received 15 June 2014; Accepted 9 July 2014; Published 3 August 2014

Academic Editor: Anna Paradowska-Stolarz

Copyright © 2014 M. Pihut et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The objective of this study was to evaluate the regression of temporomandibular pain as a result of intra-articular injections of platelet-rich plasma (PRP) to patients with temporomandibular joint dysfunction previously subjected to prosthetic treatment. Materials and Methods. The baseline study material consisted of 10 patients, both males and females, aged 28 to 53 years, previously treated due to painful temporomandibular joint dysfunction using occlusal splints. All patients were carried out to a specialist functional assessment of the dysfunction using the Polish version of the RDC/TMD questionnaire axis I and II. Intra-articular injections were preceded by a preparation of PRP. The injection sites were determined by the method used during arthroscopic surgical procedures. Following aspiration, 0.5 mL of plasma was injected into each temporomandibular joint. Results. The comparison of the intensity of pain during all examinations suggests a beneficial effect of the procedure being performed as the mean VAS score was 6.5 at examination I, 2.8 at examination II, and 0.6 at examination III. Conclusion. Application of the intra-articular injections of platelet-rich plasma into the temporomandibular joints has a positive impact on the reduction of the intensity of pain experienced by patients treated for temporomandibular joint dysfunction.