Clinical Study

CT Perfusion in the Characterisation of Renal Lesions: An Added Value to Multiphasic CT

Table 1

Characteristics of patients, renal lesions, and CT examination.

CharacteristicsAll lesions
(% or range)
Clear cell RCC
(% or range)
Chromophobe RCC
(% or range)
Papillary RCC
(% or range)
Oncocytoma
(% or range)

patients4126*55*6
Sex
 Male26 (63)16 (62)3 (60)5 (100)3 (50)
 Female15 (37)10 (38)2 (40)03 (50)
Mean age60.76 (39–86)65.29 (39–86)53.4 (39–60)58.16 (42–63)64.5 (44–80)
lesions4927 (55)10 (21)6 (12)6 (12)
Side
 Right25 (51)14 (52)6 (60)3 (50)2 (33)
 Left24 (49)13 (48)4 (40)3 (50)4 (67)
Location
 UP10 (20)6 (22)2 (20)2 (33)0
 UP-MR5 (10)3 (11)1 (10)01 (17)
 MR15 (31)7 (26)4 (40)3 (50)1 (17)
 LP-MR7 (14)6 (22)001 (17)
 LP12 (25)5 (19)3 (30)1 (17)3 (49)
Mean lesion diameter (mm)45.62 (10–128)51.25 (20–128)44.2 (10–110)26.66 (17–40)48.5 (20–116)
Pathologic tumour stage
 T1a20 (46)9 (33)5 (50)6 (100)
 T1b8 (19)6 (22)2 (20)0
 T2a2 (5)02 (20)0
 T2b2 (5)1 (4)1 (10)0
 T3a8 (19)8 (30)00
 T3b3 (6)3 (11)00
 T3c0000
 T40000
Fuhrman grade
 14 (12)3 (11)1 (17)
 221 (64)17 (63)4 (66)
 36 (18) 5 (19)1 (17)
 42 (6)2 (7)0
MVD
 Lesion439.20 (105–1230)488.66 (238–1230)412 (105–769)256 (108–482)444.3 (288–492)
 Parenchyma266.97 (71–537)222.29 (80–238)506.3 (80–537)240.16 (71–458)262.6 (162–322)
Perfusion1 CT study type
 Cine13 (26)8 (30)1 (10)2 (34)2 (34)
 Shuttle36 (74)19 (70)9 (90)4 (66)4 (66)
Multiphase CT study type
 B-CM-NG-E40 (82)22 (81)8 (80) 4 (66)6 (100)
 B-CM-NG 9 (18)5 (19)2 (20)2 (34)0
CT characteristics
 Hypervascular25 (51)17 (63)2 (20)2 (34)4 (66)
 H with necrosis14 (29)10 (37)2 (20)02 (34)
 Hypovascular10 (20)06 (60) 4 (40)0

There were 49 lesions in 41 patients; *one patient had two different histologic types of lesions: one clear cell RCC and one papillary RCC. Oncocytomas were not staged because the staging criteria only applied to RCCs. RCC: renal cell carcinoma; : number; UP: upper pole; MR: mesorenal region; LP: lower pole; MVD: microvascular density; B: baseline phase; CM: corticomedullary phase; NG: nephrographic phase; E: excretory phase; H: hypervascular.