Evaluation of Cocktails with Recombinant Proteins of Mycobacterium bovis for a Specific Diagnosis of Bovine Tuberculosis
Figure 2
IFN- responses induced by PPD-A, PPD-B, C1, and C2 in experimentally M. bovis-infected cattle () (a) and BCG-vaccinated animals () (b) at different times. The cocktails were tested at a concentration of 55 μg/mL per constitutive protein, PPD-A and PPD-B with concentration of 50 μg/mL. Aliquots of 25 μL of each antigenic preparation were added to 200 μL of blood samples. The results are expressed as mean of ODIs with standard errors. Statistical differences between responses were found by using Mann Whitney test. differs () from PDD-A and C2 values at 20 dpi for both PPD-B and C1. +: differs () from PPD-A values at 60 and 90 dpi for PPD-B, C1, and C2.
