Commercial Bovine Proteoglycan Is Highly Arthritogenic and Can Be Used as an Alternative Antigen Source for PGIA Model

<table>Arthritis incidence (a) total clinical score (b) and maximum clinical score (c) in mice with bovine proteoglycan-induced arthritis. Female BALB/c retired breeder mice were immunized with three doses of bovine PG associated with DDA adjuvant, 21-day interval. Clinical score was daily evaluated after the third immunization. <svg height="17.825001" id="M5" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 69.150002 17.825001" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to control.</table>

BioMed Research International

fig1

Figure 1

Figure 1: Commercial Bovine Proteoglycan Is Highly Arthritogenic and Can Be Used as an Alternative Antigen Source for PGIA Model 