Commercial Bovine Proteoglycan Is Highly Arthritogenic and Can Be Used as an Alternative Antigen Source for PGIA Model

<table>IgG1 and IgG2a serum levels from BALB/c retired breeder mice with bovine proteoglycan-induced arthritis. Blood samples were obtained two days before each PG+DDA immunization (days −1, 20, and 41), seven days after the third immunization (day 48), and after euthanasia (day 70). <svg height="17.825001" id="M10" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 69.150002 17.825001" width="69.150002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to day −1 of the same group.</table>

BioMed Research International

fig7

Figure 7

Figure 7: Commercial Bovine Proteoglycan Is Highly Arthritogenic and Can Be Used as an Alternative Antigen Source for PGIA Model 