Essential Oils and Their Constituents as Anticancer Agents: A Mechanistic View

Table 3

List of EO bearing plants studied for anticancer potential in in vivo models and major observations reported.

EO bearing plants	In vivo models studied	Major findings/mechanism(s) reported	Reference
Pomegranate	Skin tumour in CD1 Mice	Chemopreventive effect	[84]
Cymbopogon  citrates STAPF	Female Balb/C mice	Anticarcinogenic activity	[169]
Croton  regelianus	Sarcoma 180 murine model	Antitumour activity	[145]
Salvia  libanotica	Mice	Chemoprevention against skin papillomas	[83]
Xylopia  frutescens	Sarcoma 180 ascites tumour cells injected in mice	Tumour growth inhibition	[120]
Thymus  broussonetii	DBA-2/P815 (H2d) mouse model	Tumour reduction by injection of the EO	[96]
Plectranthus  amboinicus	B16F-10 melanoma cell line injected C57BL/6 mice	Prevention of lung metastasis	[170]
Lippia  gracilis	Sarcoma 180 bearing mice	Tumour growth inhibition	[22]
Guatteria  pogonopus	Sarcoma 180 tumour bearing Swiss mice	Tumour inhibition	[126]
Neem	RIII/Sa female mice	Tumour reduction	[160]
Curcuma  zedoaria	Mice	Angiogenesis inhibition	[171]
𝛼-Pinene from Schinus  terebinthifolius Raddi	C57Bl/6 mice with B16F10-Nex2 induced melanoma	Antimetastasis	[77]