Figure 2: Axial coregistered contrast-enhanced axial T1-weighted image (a), FLAIR image (b), and CBV map (c) from a patient affected by glioma grade IV. In the CBV map (c) warmer colors indicate higher CBV values suggesting higher perfusion and neovascularization. Comparison of CBV map (c) and contrast-enhanced axial T1-weighted image highlights a mismatch area (surrounded by the circle) corresponding to the extension of the high perfusion area outside the contrast-enhancement: this indicates a more extensive neovascularization than that shown by conventional MRI (a, b).