Evaluation of Inhibitory Effect of Recreational Drugs on Dopaminergic Terminal Neuron by PET and Whole-Body Autoradiography
Figure 4
An example of magnified view of axial QWBR images of stomach and kidney in the mice obtained at 120 minutes after administration of [18F]FDOPA. Accumulation of the radiotracer was found mainly in the renal medulla; less or none uptake of the radiotracer can be identified in the renal cortex (triangle heads). The radiotracer was accumulated in the mucosal layer of the stomach (arrow heads) but was less accumulated in the intestine. (a) Control group, (b) ketamine (55 mg/Kg), (c) cocaine (25 mg/Kg), and (d) methamphetamine (20 mg/Kg). lg: lung; li: large intestine; k-kidney; sp: spleen; st: stomach.
