BioMed Research International / 2014 / Article / Tab 2

Research Article

New Biomarkers to Predict the Evolution of In Situ Breast Cancers

Table 2

Expression of different markers in tumor cells and stroma in relapsed and nonrelapsed patients.

MarkersOverall seriesG1 + G2G3
Nonrelapsed
(median, range)
Relapsed
(median, range)
P Nonrelapsed
(n = 17)
(median, range)
Relapsed
(n = 6)
(median, range)
P Nonrelapsed
(n = 15)
(median, range)
Relapsed
(n = 6)
(median, range)
P

TG2
 Tumor cells 15 (0–100)3 (0–80)0.30620 (0–100) 11.5 (0–70)0.53210 (0–70) 2.5 (0–80)0.463
 Stroma100 (0–100)100 (70–100)0.413100 (20–100)100 (70–100)0.929100 (0–100)100 (100-100)0.206
HJURP
 Tumor cells3 (0–90)8 (0–100)0.5552 (0–90) 80 (0–100)0.06310 (0–80)0 (0–70)0.192
 Stroma0 (0–70)0 (0–80)0.3470 (0–70)55 (0–80)0.0310 (0–70) 0 (0–3)0.225
HIF-1α
 Tumor cells 0 (0–10) 1 (0–70)0.137 0 (0–10) 0 (0-0)0.439 0 (0–10)7.5 (2–70)0.024
 Stroma 0 (0–2) 0 (0–10)0.096 0 (0–2) 0 (0–10)0.7530 (0–2)2 (0–10)0.019