Research Article
New Biomarkers to Predict the Evolution of In Situ Breast Cancers
Table 4
Area under the curve (AUC) of single and combined markers in tumor and stromal cells.
| Markers | Tumor cells AUC (95% CI) | | Stroma AUC (95% CI) | |
| TG2 | 0.60 (0.40–0.81) | — | 0.56 (0.44–0.68) | — | HJURP | 0.56 (0.34–0.78) | — | 0.58 (0.39–0.77) | — | HIF-1α | 0.63 (0.45–0.81) | — | 0.63 (0.45–0.81) | — | TG2 + HJURP | 0.62 (0.41–0.82) | 0.202 | 0.65 (0.49–0.82) | 0.060 | TG2 + HIF-1α | 0.65 (0.45–0.85) | 0.682 | 0.68 (0.49–0.86) | 0.396 | HIF-1α + HJURP | 0.72 (0.55–0.90) | 0.317 | 0.80 (0.63–0.97) | 0.071 | HIF-1α + TG2 + HJURP | 0.73 (0.57–0.90) | 0.689 | 0.84 (0.70–0.98) | 0.175 |
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