Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 172620, 10 pages
http://dx.doi.org/10.1155/2014/172620
Research Article

Risk Factors for Mortality in Patients with Septic Acute Kidney Injury in Intensive Care Units in Beijing, China: A Multicenter Prospective Observational Study

1Department of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, Beijing 100038, China
2Department of Surgical Intensive Care Units, Hepatobiliary Surgery and Liver Transplant Center, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
3Center for Infectious Diseases, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China
4Department of Critical Care Medicine, Hospital affiliated to Hebei United University, Tangshan 06300, China

Received 12 May 2014; Accepted 14 June 2014; Published 7 July 2014

Academic Editor: Mingyue Zheng

Copyright © 2014 Xin Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Z. Ali, I. Khan, W. Simpson et al., “Incidence and outcomes in acute kidney injury: a comprehensive population-based study,” Journal of the American Society of Nephrology, vol. 18, no. 4, pp. 1292–1298, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. S. S. Waikar, G. C. Curhan, R. Wald, E. P. McCarthy, and G. M. Chertow, “Declining mortality in patients with acute renal failure, 1988 to 2002,” Journal of the American Society of Nephrology, vol. 17, no. 4, pp. 1143–1150, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. J. L. Xue, F. Daniels, R. A. Star et al., “Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001,” Journal of the American Society of Nephrology, vol. 17, no. 4, pp. 1135–1142, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. N. H. Lameire, A. Bagga, D. Cruz et al., “Acute kidney injury: an increasing global concern,” The Lancet, vol. 382, no. 9887, pp. 170–179, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Uchino, J. A. Kellum, R. Bellomo et al., “Acute renal failure in critically ill patients: a multinational, multicenter study,” The Journal of the American Medical Association, vol. 294, no. 7, pp. 813–818, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. E. A. J. Hoste, G. Clermont, A. Kersten et al., “RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis,” Critical Care, vol. 10, no. 3, article R73, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. M. E. Grams and H. Rabb, “The distant organ effects of acute kidney injury,” Kidney International, vol. 81, no. 10, pp. 942–948, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. J. R. Brown, R. S. Kramer, S. G. Coca, and C. R. Parikh, “Duration of acute kidney injury impacts long-term survival after cardiac surgery,” The Annals of Thoracic Surgery, vol. 90, no. 4, pp. 1142–1148, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Nejat, J. W. Pickering, P. Devarajan et al., “Some biomarkers of acute kidney injury are increased in pre-renal acute injury,” Kidney International, vol. 81, no. 12, pp. 1254–1262, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Joannidis, B. Metnitz, P. Bauer et al., “Acute kidney injury in critically ill patients classified by AKIN versus RIFLE using the SAPS 3 database,” Intensive Care Medicine, vol. 35, no. 10, pp. 1692–1702, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. (KDIGO) KDIGO, “Clinical practice guideline for acute kidney injury,” Kidney International Supplements, vol. 2, pp. 124–138, 2012. View at Google Scholar
  12. D. C. Angus, W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky, “Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care,” Critical Care Medicine, vol. 29, no. 7, pp. 1303–1310, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. S. M. Bagshaw, K. B. Laupland, C. J. Doig et al., “Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study,” Critical Care, vol. 9, no. 6, pp. R700–R709, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. W. Silvester, R. Bellomo, and L. Cole, “Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia,” Critical Care Medicine, vol. 29, no. 10, pp. 1910–1915, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. R. Jacobs, P. M. Honore, O. Joannes-Boyau et al., “Septic acute kidney injury: the culprit is inflammatory apoptosis rather than ischemic necrosis,” Blood Purification, vol. 32, no. 4, pp. 262–265, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Langenberg, L. Wan, M. Egi, C. N. May, and R. Bellomo, “Renal blood flow in experimental septic acute renal failure,” Kidney International, vol. 69, no. 11, pp. 1996–2002, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. C. Langenberg, L. Wan, S. M. Bagshaw, M. Egi, C. N. May, and R. Bellomo, “Urinary biochemistry in experimental septic acute renal failure,” Nephrology Dialysis Transplantation, vol. 21, no. 12, pp. 3389–3397, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Brenner, G. L. Schaer, D. L. Mallory, A. F. Suffredini, and J. E. Parillo, “Detection of renal blood flow abnormalities in septic and critically ill patients using a newly designed indwelling thermodilution renal vein catheter,” Chest, vol. 98, no. 1, pp. 170–179, 1990. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Oppert, C. Engel, F.-M. Brunkhorst et al., “Acute renal failure in patients with severe sepsis and septic shock—a significant independent risk factor for mortality: results from the German Prevalence Study,” Nephrology Dialysis Transplantation, vol. 23, no. 3, pp. 904–909, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. S. M. Bagshaw, S. Uchino, R. Bellomo et al., “Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes,” Clinical Journal of the American Society of Nephrology, vol. 2, no. 3, pp. 431–439, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. W. Y. Kim, J. W. Huh, C.-M. Lim, Y. Koh, and S.-B. Hong, “Analysis of progression in risk, injury, failure, loss, and end-stage renal disease classification on outcome in patients with severe sepsis and septic shock,” Journal of Critical Care, vol. 27, no. 1, pp. 104.e1–104.e7, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Plataki, K. Kashani, J. Cabello-Garza et al., “Predictors of acute kidney injury in septic shock patients: an observational cohort study,” Clinical Journal of the American Society of Nephrology, vol. 6, no. 7, pp. 1744–1751, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. E. A. J. Hoste, N. H. Lameire, R. C. Vanholder, D. D. Benoit, J. M. A. Decruyenaere, and F. A. Colardyn, “Acute renal failure in patients with sepsis in a surgical ICU: predictive factors, incidence, comorbidity, and outcome,” Journal of the American Society of Nephrology, vol. 14, no. 4, pp. 1022–1030, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. R. C. Bone, R. A. Balk, F. B. Cerra et al., “Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine,” Chest, vol. 101, no. 6, pp. 1644–1655, 1992. View at Publisher · View at Google Scholar
  25. A. S. Levey, J. Coresh, E. Balk et al., “National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification,” Annals of Internal Medicine, vol. 139, no. 2, pp. 137–147, 2003. View at Publisher · View at Google Scholar
  26. W. A. Knaus, E. A. Draper, D. P. Wagner, and J. E. Zimmerman, “APACHE II: a severity of disease classification system,” Critical Care Medicine, vol. 13, no. 10, pp. 818–829, 1985. View at Publisher · View at Google Scholar · View at Scopus
  27. J.-L. Vincent, R. Moreno, J. Takala et al., “The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure,” Intensive Care Medicine, vol. 22, no. 7, pp. 707–710, 1996. View at Publisher · View at Google Scholar · View at Scopus
  28. S. M. Bagshaw, C. George, and R. Bellomo, “Early acute kidney injury and sepsis: a multicentre evaluation,” Critical Care, vol. 12, no. 2, article R47, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Poukkanen, S. T. Vaara, V. Pettilä et al., “Acute kidney injury in patients with severe sepsis in finnish intensive care units,” Acta Anaesthesiologica Scandinavica, vol. 57, no. 7, pp. 863–872, 2013. View at Publisher · View at Google Scholar · View at Scopus
  30. “American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis,” Critical Care Medicine, vol. 20, no. 6, pp. 864–874, 1992.
  31. J. L. Koyner and P. T. Murray, “Mechanical ventilation and lung-kidney interactions,” Clinical Journal of the American Society of Nephrology, vol. 3, no. 2, pp. 562–570, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. A. S. Awad, M. Rouse, L. Huang et al., “Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury,” Kidney International, vol. 75, no. 7, pp. 689–698, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. A. H. Choudhuri, “Ventilator-Associated Pneumonia: when to hold the breath?” International Journal of Critical Infrastructure Protection, vol. 3, no. 3, pp. 169–174, 2013. View at Google Scholar
  34. S. M. Bagshaw, S. Lapinsky, S. Dial et al., “Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy,” Intensive Care Medicine, vol. 35, no. 5, pp. 871–881, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. J. A. Lopes, S. Jorge, C. Resina et al., “Acute kidney injury in patients with sepsis: a contemporary analysis,” International Journal of Infectious Diseases, vol. 13, no. 2, pp. 176–181, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. M. L. Esson and R. W. Schrier, “Diagnosis and treatment of acute tubular necrosis,” Annals of Internal Medicine, vol. 137, no. 9, pp. 744–752, 2002. View at Publisher · View at Google Scholar · View at Scopus
  37. D. Payen, A. C. de Pont, Y. Sakr, C. Spies, K. Reinhart, and J. L. Vincent, “A positive fluid balance is associated with a worse outcome in patients with acute renal failure,” Critical Care, vol. 12, no. 3, article R74, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. P. M. Honore, R. Jacobs, O. Joannes-Boyau et al., “Septic AKI in ICU patients. Diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments,” Annals of Intensive Care, vol. 1, p. 32, 2011. View at Google Scholar
  39. V. F. Seabra, E. M. Balk, O. Liangos, M. A. Sosa, M. Cendoroglo, and B. L. Jaber, “Timing of renal replacement therapy initiation in acute renal failure: a meta-analysis,” American Journal of Kidney Diseases, vol. 52, no. 2, pp. 272–284, 2008. View at Publisher · View at Google Scholar · View at Scopus
  40. R. Bellomo, C. Ronco, J. A. Kellum, R. L. Mehta, and P. Palevsky, “Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group,” Critical Care, vol. 8, no. 4, pp. R204–R212, 2004. View at Publisher · View at Google Scholar · View at Scopus
  41. R. L. Mehta, J. A. Kellum, S. V. Shah et al., “Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury,” Critical Care, vol. 11, no. 2, article R31, 2007. View at Publisher · View at Google Scholar · View at Scopus
  42. N. Y. Abosaif, Y. A. Tolba, M. Heap, J. Russell, and A. M. El Nahas, “The outcome of acute renal failure in the intensive care unit according to RIFLE: model application, sensitivity, and predictability,” American Journal of Kidney Diseases, vol. 46, no. 6, pp. 1038–1048, 2005. View at Publisher · View at Google Scholar · View at Scopus
  43. Z. Ricci, D. Cruz, and C. Ronco, “The RIFLE criteria and mortality in acute kidney injury: a systematic review,” Kidney International, vol. 73, no. 5, pp. 538–546, 2008. View at Publisher · View at Google Scholar · View at Scopus
  44. A. Kuitunen, A. Vento, R. Suojaranta-Ylinen, and V. Pettilä, “Acute renal failure after cardiac surgery: evaluation of the RIFLE classification,” Annals of Thoracic Surgery, vol. 81, no. 2, pp. 542–546, 2006. View at Publisher · View at Google Scholar · View at Scopus
  45. F. B. Rodrigues, R. G. Bruetto, U. S. Torres, A. P. Otaviano, D. M. T. Zanetta, and E. A. Burdmann, “Incidence and mortality of acute kidney injury after myocardial infarction: a comparison between KDIGO and RIFLE criteria,” PLoS ONE, vol. 8, no. 7, Article ID e69998, 2013. View at Publisher · View at Google Scholar · View at Scopus
  46. A. K. Roy, C. Mc Gorrian, C. Treacy et al., “A comparison of traditional and novel definitions (RIFLE, AKIN, and KDIGO) of acute kidney injury for the prediction of outcomes in acute decompensated heart failure,” Cardiorenal Medicine, vol. 3, no. 1, pp. 26–37, 2013. View at Google Scholar
  47. E. Rivers, B. Nguyen, S. Havstad et al., “Early goal-directed therapy in the treatment of severe sepsis and septic shock,” The New England Journal of Medicine, vol. 345, no. 19, pp. 1368–1377, 2001. View at Publisher · View at Google Scholar · View at Scopus
  48. C. Guerin, R. Girard, J. M. Selli, J. P. Perdrix, and L. Ayzac, “Initial versus delayed acute renal failure in the intensive care unit: a multicenter prospective epidemiological study,” American Journal of Respiratory and Critical Care Medicine, vol. 161, no. 3, pp. 872–879, 2000. View at Publisher · View at Google Scholar · View at Scopus
  49. J. A. Lopes, S. Jorge, C. Santos et al., “Acute kidney injury in patients with sepsis: a contemporary analysis,” International Journal of Infectious Diseases, vol. 13, pp. 176–181, 2009. View at Google Scholar