BioMed Research International

Research Article

1,3,4-Oxadiazole Derivatives: Synthesis, Characterization, Antimicrobial Potential, and Computational Studies

Table 2

Physical properties and UV-Visible analysis of synthesized 1,3,4-oxadiazole derivatives.


Compound	Molecular formula	Molecular weight	Solubility		value

6a	C₁₈H₁₆N₂O₃	308.33	DMSO, MeOH, CHCl₃	263	0.54
6b	C₁₈H₁₇N₃O₃	323.35	DMSO, MeOH, CHCl₃	278	0.42
6c	C₁₈H₁₆N₂O₃	324.33	DMSO, MeOH, CHCl₃	265	0.47
6d	C₁₈H₁₆N₂O₃	324.33	DMSO, MeOH, CHCl₃	250	0.68
6e	C₁₈H₁₅ClN₂O₃	342.78	DMSO, MeOH, CHCl₃	266	0.40
6f	C₁₈H₁₅ClN₂O₃	342.78	DMSO, MeOH, CHCl₃	265	0.43
6g	C₁₉H₁₈N₂O₃	322.36	DMSO, MeOH, CHCl₃	254	0.41
6h	C₁₈H₁₅N₃O₅	353.33	DMSO, MeOH, CHCl₃	245	0.35
13a	C₂₁H₁₄N₂O₂	326.35	DMSO, MeOH, CHCl₃	281	0.51
13b	C₂₁H₁₃ClN₂O₂	360.79	DMSO, MeOH, CHCl₃	281	0.58
13c	C₂₁H₁₃N₃O₄	371.35	DMSO, MeOH, CHCl₃	283	0.49
13d	C₂₂H₁₆N₂O₂	340.37	DMSO, MeOH, CHCl₃	281	0.55
13e	C₂₂H₁₆N₂O₄	372.37	DMSO, MeOH, CHCl₃	281	0.61
13f	C₂₁H₁₄N₂O₃	342.35	DMSO, MeOH, CHCl₃	285	0.60
13g	C₂₁H₁₃N₃O₄	371.35	DMSO, MeOH, CHCl₃	285	0.58
13h	C₂₁H₁₄N₂O₃	342.35	DMSO, MeOH, CHCl₃	283	0.67

Mobile phase for TLC: petroleum ether: ethyl acetate : MeOH (6 : 3 : 1).