Research Article

Bortezomib Treatment Produces Nocifensive Behavior and Changes in the Expression of TRPV1, CGRP, and Substance P in the Rat DRG, Spinal Cord, and Sciatic Nerve

Table 3

Percentage (±confidence limits) of TRPV1-, CGRP- and SP-LI DRG neurons in BTZ-treated rats.

Acute BTZ-treatment
CtrlBTZ

TRPV126.86 ± 0.01%29.55 ± 0.01%
CGRP25.32 ± 0.01%34.89 ± 0.01%
SP15.86 ± 0.04%14.73 ± 0.03%

Chronic BTZ-treatment
CtrlBTZ

TRPV128.65 ± 0.02%39.93 ± 0.03%
CGRP28.59 ± 0.02%34.87 ± 0.02%
SP20.60 ± 0.01%19.85 ± 0.01%