Unexpected Lack of Deleterious Effects of Uranium on Physiological Systems following a Chronic Oral Intake in Adult Rat

Table 2

Primer sequences for rat genes studied in several organs following chronic ingestion of uranium.

Genes	Forward	Reverse
HPRT	5′-GCTCGAGATGTCATGAAGGAGA-3′	5′-TCAGCGCTTTAATGTAATCCAGC-3′
	Cytokines
CCL-2	5′-CAGCCAGATGCAGTTAATGCC-3′	5′-AGCCGACTCATTGGGATCAT-3′
TNF𝛼	5′-ATCCGAGATGTGGAACTGGC-3′	5′-CGATCACCCCGAAGTTCAGTA-3′
IFN𝛾	5′-CACGCCGCGTCTTGGT-3′	5′-TCTAGGCTTTCAATGAGTGTGCC-3′
TGF𝛽	5′-TCCCAAACGTCGAGGTGAC-3′	5′-CAGGTGTTGAGCCCTTTCCA-3′
IL-10	5′-GTTGCCAAGCCTTGTCAGAAA-3′	5′-TTTCTGGCCATGGTTCTCT-3′
	Xenobiotic metabolising enzymes
CYP3A2	5′-AGTAGTGACGATTCCAACATAT-3′	5′-TCAGAGGTATCTGTGTTTCCT-3′
CYP2C11	5′-ATGGGATGCAATGGAAGGAG-3′	5′-TCTTGCCCATCCCAAAAGTC-3′
ST1A1	5′-AGGGTGGCAAGCTAGAGAAGTG-3′	5′-GAGGGAACCCCTGGACATTT-3′
GSTA2	5′-TTGACATGTATTCAGAGGGT-3′	5′-TTGTTTTGCATCCATGGCTG-3′
UGT1A1	5′-TGGCATCCCCAAAACGATCT-3′	5′-GGAACCGGAGTGTGTGATGAA-3′
UGT2B1	5′-TGGAGAACATGGTGTAGTGGT-3′	5′-TTGGCTTTTTCTTCAGTAGTCAGG-3′
MDR1	5′-ATCAACTCGCAAAAGCATCC-3′	5′-AATTCAACTTCAGGATCCGC-3′
MRP2	5′-TTCGAAGCTGGATGATGTGTTT-3′	5′-GCCATGCAGATCATGACAAGAG-3′
	Enzymes of cholesterol metabolism
HMGR	5′-GGCGGGTCCTGCAAGTG-3′	5′-GCAGGTGAGCGGGTGAGA-3′
CYP27A1	5′-GGAAGGTGCCCCAGAACAA-3′	5′-GCGCAGGGTCTCCTTAATCA-3′
CYP7A1	5′-CCAAGTCAAGTGTCCCCCTCTA-3′	5′-GACTCTCAGCCGCCAAGTG-3′
CYP8B1	5′-GTACACATGGACCCCGACATC-3′	5′-GGGTGCCATCAGGGTTGAG-3′
CYP7B1	5′-TCAGATGCAAAGACGGTCAGA-3′	5′-TTCATGCCCGTAGTATTTTTTCAG-3′
ACAT2	5′-GCCCCAGCCGACATTTT-3′	5′-GTGCAGTGTGAAGCCTTGACTT-3′
ABCA1	5′-ATCTCATAGTATGGAAGAATGTGAAGCT-3′	5′-CGTACAACTATTGTATAACCATCTCCAAA-3′
ABCG5	5′-CGCAGGAACCGCATTGTAA-3′	5′-TGTCGAAGTGGTGGAAGAGCT-3′
LDL-r	5′-CAGCCGATGCATTCCTGACT-3′	5′-AGTTCATCCGAGCCATTTTCAC-3′
SR-B1	5′-GTTGGTCACCATGGGCCA-3′	5′-CGTAGCCCCACAGGATCTCA-3′
ApoA1	5′-AATGGGACAGGGTGAAGGA-3′	5′-TGAACCCAGAGTGTCCCAGTT-3′
ApoB	5′-TCCTAACATCATTGTGCCTTCAT-3′	5′-CCTTGAAATCTGGGAGGGAAAACT-3′
LXR𝛼	5′-AGCAACAGTGTAACAGGCGCT-3′	5′-GTGCAATGGGCCAAGGC-3′
FXR	5′-TGACAAAGAAGCCGCGAAT-3′	5’-TGTAATGGTACCCAGAGGCCC-3′
RXR𝛼	5′-CGCAAAGACCTGACCTACACC-3′	5′-TCCTCCTGCACGGCTTCCC-3′
SREBP2	5′-AGCTGGCAAATCAGAAAAACAAG-3′	5′-CGATCTTCAAGTCCACATCACTGT-3′
PPAR𝛼	5′-TCTCTTCCCAAAACTCCTTCA-3′	5′-GCACGAGCTGCGCATGCTC-3′
PPAR𝛾	5′-TCA TGA CCA GGG AGT TCC TCA-3′	5′-TCATCTAATTCCAGTGCATTGAACTT-3′