Research Article

A Promising Approach to Provide Appropriate Colon Target Drug Delivery Systems of Vancomycin HCL: Pharmaceutical and Microbiological Studies

Table 2

Results of kinetics study.

FormulaCorrelation coefficients ( ) Korsemayer’sslope ( ) in hourMDT in hourDR after 9 hours %
Zero orderFirst orderHixon-Crowell Higuchi’s model

F60.9520.5370.9330.9820.4321.828.2561.0029.71
F9 0.8200.5070.8330.8830.52 3.724.9690.6734.00
F100.8820.5290.8470.9320.50 4.806.2881.9131.36
F110.9020.5400.8700.9470.51 5.686.7477.9128.16
F120.8260.5830.7710.8890.56 8.40 4.8374.9931.16
F130.9470.5720.9170.9780.60>247.9746.4527.89
F140.9230.5650.9320.9620.57>247.1952.8228.68
F150.9260.5580.8870.9610.5623.257.4055.2128.66
F160.9400.5590.9120.9740.60>247.9553.3228.85
F170.8250.5350.7950.8900.5423.234.3765.3233.87
F180.8640.5280.8390.9200.52 8.925.0570.7632.97
F190.9230.5520.8410.9630.69>246.8042.0025.00
F200.9400.5530.8590.9450.58>247.6423.0022.63