Antidiabetic Activity of Artemisia amygdalina Decne in Streptozotocin Induced Diabetic Rats

Table 5

Effect of extracts of Artemisia amygdalina and glibenclamideon body weight in streptozotocin induced diabetic rats.

Groups	Body weight (g)
	0th day	7th day	14th day	% variation
Normal	120±1.79	135±3.13	155±2.68	29.16
Diabetic control	125±1.34	118±1.79	107±3.13	−14.4
Hydroethanolic extract (250 mg/kg b. w)	127±2.24	132±2.24	139±3.58^∗∗	9.44
Hydroethanolic extract (500 mg/kg b. w)	122±2.68	128±3.13	135±2.24^∗∗	10.65
Methanolic extract (250 mg/kg b. w)	125±3.13	130±3.58	137±4.92^∗∗	9.6
Methanolic extract (500 mg/kg b. w)	123±2.24	130±3.58	140±5.37^∗∗	13.82
Glibenclamide (3 mg/kg b. w)	125±1.79	133±2.68	142±3.13^∗∗	13.6

The values are expressed as mean ± SEM; 𝑛=5 in each group. ^∗∗𝑃<0.01 as compared with diabetic control at the same time (one-way ANOVA followed by Dunnett’s multiple comparison test).