Comparative Assessment of Lymph Node Micrometastasis in Cervical, Endometrial and Vulvar Cancer: Insights on the Real Time qRT-PCR Approach versus Immunohistochemistry, Employing Dual Molecular Markers
Figure 2
Immunohistochemical assessment for micrometastasis of representative lymph nodes by CK19 and CA9 expression. (a) Lymph node from patient IE-12 with endometrial carcinoma, positive for micrometastasis, exhibiting CK19 expression by the clusters of metastatic epithelial cells. (b) Lymph node from patient IC-8 with cervical carcinoma, positive for micrometastasis, exhibiting CA9 expression by the isolated metastatic epithelial cells. (c) Lymph node from patient IE-12 with endometrial carcinoma, negative for micrometastasis, stained with the anti-CK19 antibody. (d) Lymph node from patient IC-23 with cervical carcinoma, negative for micrometastasis and stained with the anti-CA9 antibody.
