Diverse Effects of ANXA7 and p53 on LNCaP Prostate Cancer Cells Are Associated with Regulation of SGK1 Transcription and Phosphorylation of the SGK1 Target FOXO3A
Figure 5
Both images were created using IPA. The left image shows ANXA7, p53, and PTEN connections to the network that involves FOXO3A and putative FOXO3A-phosphorylating kinases; the phosphorylation involving relationships are highlighted (yellow edges). The right image shows a schematic pathway that was created using PI3K/Akt canonical pathway as a template and was enriched by putative ANXA7 and SGK1 connections; FOXO3A and the FOXO3A-phosphorylating SGK1 and Akt are highlighted in yellow.
