Syn-Lethality: An Integrative Knowledge Base of Synthetic Lethality towards Discovery of Selective Anticancer Therapies

Table 1

Representative entries for human cancer Syn-Lethality database.

Representative entries	Contents
SL pairs information	Gene names A and B, SL pairs mechanism, and related pathway
SL pairs annotation	Gene symbol, full name, Entrez ID, KEGG-link
Type of gene alterations	Mutation, activation, inactivation, overexpression, deficient
Type of gene involved; in SL pairs	Tumor suppressor gene, oncogene
Data source	Human cancer, inferred from yeast
Cancer type	All kinds of cancer
Screening methods	shRNA, siRNA, anticancer compound
The literature search	PMID