Table 3: Total statistics for human cancer Syn-Lethality database.

Content Number Comments

SL pairs for human cancer from the literatures 113 NCBI PubMed abstracts
SL pairs for human cancer inferred from yeast 1114 Prediction according the orthologous
Screening methods 3 siRNA, shRNA, anticancer compound screening
Type of gene alteration 5 Mutation, deficient, inactivation, activation, overexpression
Annotated human genes 647 Only one gene of SL pairs related to human cancer also counted
Annotated signalling pathways of human genes 647 KEGG pathways