Crude Extracts from Lycium barbarum Suppress SREBP-1c Expression and Prevent Diet-Induced Fatty Liver through AMPK Activation

Table 1

Effect of LBP on body compositions of HFD-fed mice.

Variables	LFD	HFD	100 LBP + HFD
Initial body weight (g)	23.1±0.23	23.8±0.29	23.6±0.23
Final body weight (g)	30.0±0.46	44.6±1.01	33.5±1.43^#
Water intake (mL/d/mouse)	6.97±0.16	8.41±0.17	7.26±0.05
Abdominal circumference (cm)	7.63±0.13	10.83±0.08	7.98±0.14^#
BMI (g/cm^2)	0.32±0.07	0.58±0.10	0.37±0.09^#
Liver weight (g)	1.06±0.04	2.31±0.18	1.25±0.05^#
White fat weight (g)	0.71±0.06	4.40±0.22	1.66±0.08^##
Brown fat weight (g)	0.24±0.03	0.09±0.01	0.30±0.05^##

Data are expressed as means ± SEM (𝑛=10 per group), ^#𝑃<0.05 and ^##𝑃<0.01, compared to HFD group. LFD: low-fat diet; HFD: high-fat diet; 100 LBP + HFD: 100 mg/kg LBP plus high-fat diet; BMI: body mass index.