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BioMed Research International
Volume 2014, Article ID 203906, 6 pages
Review Article

The Role of MRI in Prostate Cancer Active Surveillance

1Molecular Pharmacology Section, Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20852, USA
2Molecular Imaging Program, National Cancer Institute, Bethesda, MD 20852, USA
3Clinical Pharmacology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20852, USA

Received 13 June 2014; Revised 22 August 2014; Accepted 23 August 2014; Published 30 November 2014

Academic Editor: Jurgen Futterer

Copyright © 2014 Linda M. Johnson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Prostate cancer is the most common cancer diagnosis in American men, excluding skin cancer. The clinical behavior of prostate cancer varies from low-grade, slow growing tumors to high-grade aggressive tumors that may ultimately progress to metastases and cause death. Given the high incidence of men diagnosed with prostate cancer, conservative treatment strategies such as active surveillance are critical in the management of prostate cancer to reduce therapeutic complications of radiation therapy or radical prostatectomy. In this review, we will review the role of multiparametric MRI in the selection and follow-up of patients on active surveillance.