Research Article

Bioassay Directed Isolation and Biological Evaluation of Compounds Isolated from Rubus fairholmianus Gard.

Table 1

DPPH and ABTS radical scavenging activities of fractions and compounds of R. fairholmianus.

Fractions
and compounds
DPPH radical
scavenging activity
(IC50: µg/mL)
ABTS radical cation
scavenging activity
(µM Trolox equivalents/g extract)

114.732240.99 ± 32.55
217.951363.49 ± 23.38
318.703749.60 ± 5.85
420.313074.61 ± 35.56
57.163496.48 ± 51.96
618.014478.60 ± 35.56
79.553374.98 ± 23.38
825.562335.49 ± 40.92
93.614650.72 ± 15.47
1015.364377.35 ± 11.69
1121.972234.24 ± 5.85
1217.612122.86 ± 32.55
1327.791140.74 ± 30.93
1424.634765.47 ± 47.85
1516.394974.72 ± 45.66
1613.413860.98 ± 42.15
Compound 13.235344.45 ± 24.94
Compound 25.099233.20 ± 54.32a
Compound 310.766421.23 ± 84.46d
Compound 48.578754.78 ± 42.29b
Compound 512.355656.32 ± 38.53
Compound 69.437455.54 ± 62.98c
Butylated hydroxy toluene (BHT)13.18
Butylated hydroxy anisole (BHA)4.88
Rutin5.81
Quercetin4.12

Values are mean of triplicate determination   ±  standard deviation. Statistically significant at where a > b > c > d.