Amelioration of Colitis in Mouse Model by Exploring Antioxidative Potentials of an Indigenous Probiotic Strain of Lactobacillus fermentum Lf1

Figure 1

Relative expression of “Nrf2” and MDA inhibitory effect by Lactobacilli strains in HT-29 cell lines under H₂O₂ stress conditions. Data are represented as mean ± SD; number of RT-qPCR experiments (𝑛) = 3. (a) Comparative analysis of relative expression of “Nrf2” in HT-29 on challenge with different strains of probiotic Lactobacilli and H₂O₂ stress. ∗Data are significantly different compared with control (𝑃<0.001; Bonferroni post hoc test). (b) Inhibitory effect of various probiotic Lactobacillus cultures on lipid peroxidation in HT-29 cells. Data are significantly different compared with control (H₂O₂ alone) (^∗𝑃<0.001; ^∗∗𝑃<0.01; Bonferroni post hoc test).

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