The Effects of Acute Hydrogen Sulfide Poisoning on Cytochrome P450 Isoforms Activity in Rats

Table 1

Regression equation and correlation coefficient for six probe drugs.

Probe drugs	Liner range (ng/mL)	Regression equation	Correlation coefficient
Bupropion	10–2000	𝑦=0.002629𝑥+0.055076	0.997233
Metoprolol	10–2000	𝑦 = 0.003557𝑥 + 0.110593	0.997110
Midazolam	10–2000	𝑦 = 0.003584𝑥 + 0.146928	0.996311
Phenacetin	10–2000	𝑦 = 0.000656𝑥  − 0.001949	0.998495
Omeprazole	10–2000	𝑦 = 0.000602𝑥 + 0.032108	0.996069
Tolbutamide	10–2000	𝑦 = 0.000576𝑥 + 0.012733	0.995463

𝑦: peak area ratio of probe drugs versus IS; 𝑥: concentration of probe drugs.