Effects of Parity and Serum Prolactin Levels on the Incidence and Regression of DMBA-Induced Tumors in OFA hr/hr Rats

<table>Mammary <i>β</i>-casein content at the end of the experiment from DMBA-treated rats. (a) Nulliparous rats (Null) had significantly lower mammary <i>β</i>-casein than rats implanted with 17-<i>β</i> estradiol in the arcuate nucleus (I) or rats after a cycle of pregnancy and lactation (PL) <svg height="17.825001" id="M20" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 96.612503 17.825001" width="96.612503" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. (b) When classified depending on the development (T) or absence (NT) of mammary tumors, the implanted and primiparous rats developing tumors showed significantly higher levels of mammary <i>β</i>-casein than the corresponding tumor-free rats <svg height="17.825001" id="M21" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 66.324997 17.825001" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. Comparisons were performed by ANOVA I.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Effects of Parity and Serum Prolactin Levels on the Incidence and Regression of DMBA-Induced Tumors in OFA hr/hr Rats 