Impact of Hemodialysis on Dyspnea and Lung Function in End Stage Kidney Disease Patients

Table 3

Pattern of breathing and arterial blood gases of the 25 ESKD patients before and after dialysis.

	Before dialysis; 𝑛=25	After dialysis; 𝑛=25	𝑃 value
𝑉𝑇 (lt)	0.7 ± 0.2	0.6 ± 0.2	NS
𝑇𝐸 (sec)	1.8 ± 0.5	1.7 ± 0.5	NS
𝑇𝐼 (sec)	1.5 ± 0.3	1.4 ± 0.3	NS
𝑉𝑇/𝑇𝐼 (lt/sec)	0.5 ± 0.2	0.4 ± 0.2	NS
𝑇𝐼/𝑇TOT (sec)	0.4 ± 0.04	0.5 ± 0.03	NS
𝑉𝐸 (lt/min)	13.0 ± 4.0	12.0 ± 5.0	NS
RR (breaths/min)	19.0 ± 5.0	20.0 ± 4.0	NS
𝑃0.1 (cm H2O)	3.0 ± 0.3	0.7 ± 0.2	<0.001
𝑃0.1/𝑉𝑇% VC pred., acc	0.2 ± 0.1	0.05 ± 0.02	<0.001
pH	7.4 ± 0.1	7.5 ± 0.1	<0.001
PaO2 (mm Hg)	98.0 ± 11.0	97.0 ± 14.0	NS
PaCO2 (mm Hg)	31.0 ± 4.0	33.0 ± 5.0	0.02
HCO3 (mmol)	20.0 ± 4.0	25.0 ± 3.0	<0.001

Values are mean ± SD obtained in the seated position. Unless otherwise specified, values are expressed as % predicted. Statistical significance tested with Student’s paired 𝑡-test before and after dialysis. 𝑉_𝑇: tidal volume; 𝑉_𝐸: minute ventilation; 𝑇_𝐸: duration of expiration; 𝑇_𝐼: duration of inspiration; 𝑇_TOT: total cycle duration; 𝑉_𝑇/𝑇_𝐼: mean inspiratory flow; 𝑇_𝐼/𝑇_TOT: duty cycle; 𝑓: frequency of breathing; 𝑃_0.1: mouth occlusion pressure; % pred. VC: vital capacity % predicted; PaO₂: arterial pressure tension of oxygen; PaCO₂: arterial pressure tension of carbon dioxide; HCO₃: bicarbonate anion.