ECM Inspired Coating of Embroidered 3D Scaffolds Enhances Calvaria Bone Regeneration
Figure 9
Representative histological images of one animal from each group (Masson-Goldner trichrome staining). (a) Schematic drawing of the histological sample preparation. (b) Empty defect. (c) Autologous bone. (d) PCL noncoated. (e) PCL coll I/cs coated. I: frontal plane with the defect area marked by the 13 mm line (1x). II: transversal plane with the defect area is marked by the orange semicircle (1x). PCL scaffold is marked in black. III: enlarged section of the defect zone (20x). obl: osteoblast, ocy: osteocyte, o: osteon (orange), hc: Haversian canal, f: fibroblast, bv: blood vessel with erythrocyte, and fct: firm connective tissue.
