Research Article

CNB-001 a Novel Curcumin Derivative, Guards Dopamine Neurons in MPTP Model of Parkinson’s Disease

Figure 5

Photomicrograph of SN sections illustrating TH-immunoreactive (TH-ir) neurons. (a) (4X) MPTP administration (F) significantly degenerated TH-ir neurons. Pretreatment with CNB-001 (G) significantly increased TH positivity as compared to MPTP group. (b) Quantification of TH positive neurons was performed by counting number of TH-ir neurons and values are expressed as mean ± SD of three animals per group. compared to control, compared to MPTP.
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