Fenoldopam 0.1 mcg/kg/h IV 1-2 hours before and 6 hours after
NAC 600 mg po bid
NSS or D5W 1 mL/kg/h 1-2 hours before and 6–12 hours after
↑Cr ≥25%/1–3 days or ↑Cr ≥0.5/1–3 days
*Cr 1.53 versus 1.46
20.0 versus 11.4
0.40
ND
*Mean GFR data is not available. Data is shown as mean serum creatinine in mg/dL.
**Percentage of RRT requirement data in each group is not available. Data is shown as percentage of RRT requirement in all patients. bid: twice daily; CAG: coronary angiography; CHF: congestive heart failure; CI-AKI: contrast-induced acute kidney injury; Cr: creatinine; g: gram; D5W: 5% dextrose solution; h: hour; IONICM: isoosmolarity nonionic contrast media; IV: intravenous; kg: kilogram body weight; LONICM: low osmolarity nonionic contrast media; mcg: microgram; mg: milligram; mL: milliliter; NAC: N-acetylcysteine; ND: no data; NSS: normal saline solution; N/2: 0.45% NaCl; po: per oral route; q12h: every 12 hours; RRT: renal replacement therapy.