Protective Effect of Ethanolic Extract of Tabernaemontana divaricata (L.) R. Br. against DEN and Fe NTA Induced Liver Necrosis in Wistar Albino Rats

Table 2

Changes in the activities of liver marker enzymes in liver.

Particulars	Group I	Group II	Group III	Group IV	Group V	Group VI	Group VII
AST	77.94 ± 2.48^a	44.9 ± 1.71^b	68.47 ± 1.79^c	72.66 ± 1.77^d	76.46 ± 1.17^a	76.71 ± 1.3^a	75.85 ± 1.1^a
ALT	36.25 ± 0.37^a	26.94 ± 0.71^b	30.17 ± 0.72^c	35.37 ± 0.94^a	36.14 ± 0.46^a	34.82 ± 0.46^a	33.73 ± 0.73^d
ALP	12.95 ± 0.49^a	7.86 ± 0.66^b	9.93 ± 0.39^c	12.85 ± 0.34^a	12.0 ± 0.4^a	12.32 ± 0.34^a	12.32 ± 0.57^a
ACP	9.39 ± 0.1^a	4.67 ± 0.15^b	7.51 ± 0.12^c	9.02 ± 0.07^d	9.45 ± 0.16^a	9.32 ± 0.23^a	9.27 ± 0.15^a
LDH	86.51 ± 0.76^a	52.33 ± 0.64^b	66.28 ± 0.65^c	83.71 ± 0.94^d	84.98 ± 0.78^e	85.58 ± 0.5^e	85.36 ± 0.88^a
5′ nucleotidase	8.63 ± 0.04^a	5.09 ± 0.05^b	6.4 ± 0.06^c	8.14 ± 0.07^d	8.44 ± 0.17^a	8.53 ± 0.05^a	8.31 ± 0.06^d

Values are expressed as mean ± SD (𝑛=6).
Values not sharing the common superscript differ significantly (DMRT).
Units are as follows:
AST, ALT, LDH—nmoles of pyruvate liberated/min/mg protein.
ALP, ACP—nmoles of phenol liberated/min/mg protein.
5′ nucleotidase—nmoles of phosphate liberated/min/mg protein.