Research Article

Protective Effect of Ethanolic Extract of Tabernaemontana divaricata (L.) R. Br. against DEN and Fe NTA Induced Liver Necrosis in Wistar Albino Rats

Table 4

Changes in the level of nonenzymatic antioxidants in liver.

ParticularsControl (Group I)DEN + Fe-NTA (Group II)DEN & Fe-NTA + plant extract (200 mg/kg) (Group III) DEN & Fe-NTA + plant extract (400 mg/kg) (Group IV) Plant extract alone (200 mg/kg) (Group V) Plant extract alone (400 mg/kg) (Group VI) DEN & Fe-NTA + Std drug (GroupVII)

GSH21.28 ± 0.45a11.76 ± 0.59b16.26 ± 0.65c19.81 ± 0.14d20.74 ± 0.42a21.34 ± 0.32a20.02 ± 0.34d
TSH6.7 ± 0.07a3.5 ± 0.05b4.46 ± 0.06c6.68 ± 0.06a6.5 ± 0.04a6.56 ± 0.08a6.57 ± 0.08a
Vitamin C3.0 ± 0.1a1.82 ± 0.18b2.8 ± 0.11c3.02 ± 0.12a3.09 ± 0.05a3.13 ± 0.12a2.84 ± 0.11d

Values are expressed as mean ± SD ( ).
Values not sharing the common superscript differ significantly (DMRT).
The units were expressed in µg/mg protein.