Protective Effect of Ethanolic Extract of Tabernaemontana divaricata (L.) R. Br. against DEN and Fe NTA Induced Liver Necrosis in Wistar Albino Rats
Table 4
Changes in the level of nonenzymatic antioxidants in liver.
Particulars
Control (Group I)
DEN + Fe-NTA (Group II)
DEN & Fe-NTA + plant extract (200 mg/kg) (Group III)
DEN & Fe-NTA + plant extract (400 mg/kg) (Group IV)
Plant extract alone (200 mg/kg) (Group V)
Plant extract alone (400 mg/kg) (Group VI)
DEN & Fe-NTA + Std drug (GroupVII)
GSH
21.28 ± 0.45a
11.76 ± 0.59b
16.26 ± 0.65c
19.81 ± 0.14d
20.74 ± 0.42a
21.34 ± 0.32a
20.02 ± 0.34d
TSH
6.7 ± 0.07a
3.5 ± 0.05b
4.46 ± 0.06c
6.68 ± 0.06a
6.5 ± 0.04a
6.56 ± 0.08a
6.57 ± 0.08a
Vitamin C
3.0 ± 0.1a
1.82 ± 0.18b
2.8 ± 0.11c
3.02 ± 0.12a
3.09 ± 0.05a
3.13 ± 0.12a
2.84 ± 0.11d
Values are expressed as mean ± SD (). Values not sharing the common superscript differ significantly (DMRT). The units were expressed in µg/mg protein.