Research Article

Endothelium-Independent Vasorelaxant Effects of Hydroalcoholic Extract from Nigella sativa Seed in Rat Aorta: The Roles of Ca2+ and K+ Channels

Figure 4

Effect of Nigella sativa seed extract (14 mg/mL) on endothelium-denuded rat aortic rings (−E) contracted with PE (  M), in the presence of diltiazem (  M) (−E + Dil), after ruthenium red (  M) (−E + Dil + RR) or heparin (50 mg/L) (−E + Dil + HP) pretreatment. Data are expressed as mean ± S.E.M. ( ). , compared to −En; compared to −E + Dil.
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