BioMed Research International / 2014 / Article / Tab 2

Review Article

The Role of MicroRNAs in Ovarian Cancer

Table 2

Potential diagnostic miRs for ovarian cancer.

ReferenceSampleElevated miRDecreased miRTumor histology ()Control ()

[47], 2008Exosome (serum)miR-21, miR-141, miR-200a, miR-200c, miR-200b, miR-203, miR-205, miR-214SAC (50)BOA (10), HC (10)
[48], 2009SerummiR-21, miR-92, miR-93, miR-126, miR-29amiR-155, miR-127, miR-99bSAC (17), CAC (6), EAC or MAC (5)HC (15)
[49], 2010Whole bloodmiR-30c-1-3pmiR-181a-3p, miR-342-3p, miR-450-5pSAC (21), EAC (2), other (1) (relapsed)HC (15)
[50], 2012SerummiR-200a, miR-200b, miR-200cSAC (28)HC (28)
[51], 2013SerummiR-132, miR-26a, let-7b, miR-145SAC (18)HC (12)
[52], 2013 PlasmamiR-16, miR-21, miR-191 (CAC, EAC)SAC (21), CAC (7), EAC (6), other (1)EM (33), HC (20)
miR-16, miR-191, miR-4284 (SAC)
[53], 2013PlasmamiR-205let-7fSAC (179), CAC (15), EAC (86), MAC (33), other (47)HC (200)

SAC: serous adenocarcinoma; CAC: clear cell adenocarcinoma; EAC: endometrioid adenocarcinoma; MAC: mucinous adenocarcinoma; BOA: benign ovarian adenoma; HC: healthy control; EM: endometriosis.

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