Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014 (2014), Article ID 256879, 7 pages
http://dx.doi.org/10.1155/2014/256879
Research Article

Association between Oxidative Stress and Outcome in Different Subtypes of Acute Ischemic Stroke

1Department of Neurology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung, Taiwan
2Department of Biological Science, National Sun Yat-Sen University, Taiwan
3Department of Neurosurgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung, Taiwan
4Department of Radiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung, Taiwan
5Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung, Taiwan
6Department of Emergency Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung District, Kaohsiung, Taiwan

Received 27 February 2014; Accepted 7 April 2014; Published 8 May 2014

Academic Editor: Hung-Chen Wang

Copyright © 2014 Nai-Wen Tsai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Suwanwela and W. J. Koroshetz, “Acute ischemic stroke: overview of recent therapeutic developments,” Annual Review of Medicine, vol. 58, pp. 89–106, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. Samson, B. Lapergue, and H. Hosseini, “Inflammation and ischaemic stroke: current status and future perspectives,” Revue Neurologique, vol. 161, no. 12, pp. 1177–1182, 2005. View at Google Scholar · View at Scopus
  3. A. Cherubini, C. Ruggiero, M. C. Polidori, and P. Mecocci, “Potential markers of oxidative stress in stroke,” Free Radical Biology and Medicine, vol. 39, no. 7, pp. 841–852, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Goodman, P. Sharma, and A. Ferro, “The genetics of aspirin resistance,” International Journal of Clinical Practice, vol. 61, no. 5, pp. 826–834, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. L. C. Álvaro-González, M. M. Freijo-Guerrero, and F. Sádaba-Garay, “Inflammatory mechanisms, arteriosclerosis and ischemic stroke: clinical data and perspectives,” Revista de Neurologia, vol. 35, no. 5, pp. 452–462, 2002. View at Google Scholar · View at Scopus
  6. A. Chamorro, “Role of inflammation in stroke and atherothrombosis,” Cerebrovascular Diseases, vol. 17, no. 3, supplement, pp. 1–5, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. T. J. Guzik, R. Korbut, and T. Adamek-Guzik, “Nitric oxide and superoxide in inflammation and immune regulation,” Journal of Physiology and Pharmacology, vol. 54, no. 4, pp. 469–487, 2003. View at Google Scholar · View at Scopus
  8. M. Lafon-Cazal, S. Pietri, M. Culcasi, and J. Bockaert, “NMDA-dependent superoxide production and neurotoxicity,” Nature, vol. 364, no. 6437, pp. 535–537, 1993. View at Publisher · View at Google Scholar · View at Scopus
  9. C. A. Piantadosi and J. Zhang, “Mitochondrial generation of reactive oxygen species after brain ischemia in the rat,” Stroke, vol. 27, no. 2, pp. 327–332, 1996. View at Google Scholar · View at Scopus
  10. S. A. Lipton and P. A. Rosenberg, “Mechanisms of disease: excitatory amino acids as a final common pathway for neurologic disorders,” New England Journal of Medicine, vol. 330, no. 9, pp. 613–622, 1994. View at Publisher · View at Google Scholar · View at Scopus
  11. C. E. Walder, S. P. Green, W. C. Darbonne et al., “Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase,” Stroke, vol. 28, no. 11, pp. 2252–2258, 1997. View at Google Scholar · View at Scopus
  12. Y. Matsuo, T. Kihara, M. Ikeda, M. Ninomiya, H. Onodera, and K. Kogure, “Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: effect of neutrophil depletion on extracellular ascorbyl radical formation,” Journal of Cerebral Blood Flow and Metabolism, vol. 15, no. 6, pp. 941–947, 1995. View at Google Scholar · View at Scopus
  13. H. Sies, “Oxidative stress: oxidants and antioxidants,” Experimental Physiology, vol. 82, no. 2, pp. 291–295, 1997. View at Google Scholar · View at Scopus
  14. F. Karatas, M. Karatepe, and A. Baysar, “Determination of free malondialdehyde in human serum by high-performance liquid chroma tography,” Analytical Biochemistry, vol. 311, no. 1, pp. 76–79, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. S. E. Gariballa, T. P. Hutchin, and A. J. Sinclair, “Antioxidant capacity after acute ischaemic stroke,” QJM, vol. 95, no. 10, pp. 685–690, 2002. View at Google Scholar · View at Scopus
  16. M. Spranger, S. Krempien, S. Schwab, S. Donneberg, and W. Hacke, “Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury: correlation with clinical course and infarct size,” Stroke, vol. 28, no. 12, pp. 2425–2428, 1997. View at Google Scholar · View at Scopus
  17. C.-Y. Chang, Y.-C. Lai, T.-J. Cheng, M.-T. Lau, and M.-L. Hu, “Plasma levels of antioxidant vitamins, selenium, total sulfhydryl groups and oxidative products in ischemic-stroke patients as compared to matched controls in Taiwan,” Free Radical Research, vol. 28, no. 1, pp. 15–24, 1998. View at Google Scholar
  18. J. M. Leppälä, J. Virtamo, R. Fogelholm, D. Albanes, and O. P. Heinonen, “Different risk factors for different stroke subtypes: association of blood pressure, cholesterol, and antioxidants,” Stroke, vol. 30, no. 12, pp. 2535–2540, 1999. View at Google Scholar · View at Scopus
  19. H. P. Adams Jr., B. H. Bendixen, L. J. Kappelle et al., “Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial,” Stroke, vol. 24, no. 1, pp. 35–41, 1993. View at Google Scholar · View at Scopus
  20. R. L. Sacco, R. Adams, G. Albers et al., “Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association council on stroke—co-sponsored by the council on cardiovascular radiology and intervention. The American Academy of Neurology affirms the value of this guideline,” Stroke, vol. 37, no. 2, pp. 577–617, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. G. Sulter, C. Steen, and J. De Keyser, “Use of the Barthel Index and Modified Rankin Scale in acute stroke trials,” Stroke, vol. 30, no. 8, pp. 1538–1541, 1999. View at Google Scholar · View at Scopus
  22. T.-L. Huang, C.-W. Liou, and T.-K. Lin, “Serum thiobarbituric acid-reactive substances and free thiol levels in schizophrenia patients: effects of antipsychotic drugs,” Psychiatry Research, vol. 177, no. 1-2, pp. 18–21, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Demirkaya, M. A. Topcuoglu, A. Aydin, U. H. Ulas, A. I. Isimer, and O. Vural, “Malondialdehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia,” European Journal of Neurology, vol. 8, no. 1, pp. 43–51, 2001. View at Publisher · View at Google Scholar · View at Scopus
  24. P. C. Sharpe, C. Mulholland, and T. Trinick, “Ascorbate and malondialdehyde in stroke patients,” Irish Journal of Medical Science, vol. 163, no. 11, pp. 488–491, 1994. View at Google Scholar · View at Scopus
  25. M. C. Polidori, A. Cherubini, W. Stahl, U. Senin, H. Sies, and P. Mecocci, “Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: relationship to early outcome,” Free Radical Research, vol. 36, no. 3, pp. 265–268, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. G. A. Lammie, F. Brannan, J. Slattery, and C. Warlow, “Nonhypertensive cerebral small-vessel disease: an autopsy study,” Stroke, vol. 28, no. 11, pp. 2222–2229, 1997. View at Google Scholar · View at Scopus
  27. P. M. Rothwell, “Atherothrombosis and ischaemic stroke,” British Medical Journal, vol. 334, no. 7590, pp. 379–380, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. N. W. Tsai, L. H. Lee, C. R. Huang et al., “Statin therapy reduces oxidized low density lipoprotein level, a risk factor for stroke outcome,” Critical Care, vol. 18, no. 1, article R16, 2014. View at Google Scholar
  29. J. de Keyser, N. de Klippel, H. Merkx, M. Vervaeck, and L. Herroelen, “Serum concentrations of vitamins A and E and early outcome after ischaemic stroke,” The Lancet, vol. 339, no. 8809, pp. 1562–1565, 1992. View at Publisher · View at Google Scholar · View at Scopus
  30. J. S. Leinonen, J.-P. Ahonen, K. Lönnrot et al., “Low plasma antioxidant activity is associated with high lesion volume and neurological impairment in stroke,” Stroke, vol. 31, no. 1, pp. 33–39, 2000. View at Google Scholar · View at Scopus
  31. T. T. Idicula, J. Brogger, H. Naess, U. Waje-Andreassen, and L. Thomassen, “Admission C-reactive protein after acute ischemic stroke is associated with stroke severity and mortality: the ‘Bergen stroke study’,” BMC Neurology, vol. 9, article 18, 2009. View at Publisher · View at Google Scholar · View at Scopus
  32. M. S. V. Elkind, J. Cheng, T. Rundek, B. Boden-Albala, and R. L. Sacco, “Leukocyte count predicts outcome after ischemic stroke: the Northern Manhattan Stroke Study,” Journal of Stroke and Cerebrovascular Diseases, vol. 13, no. 5, pp. 220–227, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. N. W. Tsai, L. H. Lee, and C. R. Huang, “The association of statin therapy and high-sensitivity C-reactive protein level for predicting clinical outcome in acute non-cardio-embolic ischemic stroke,” Clinica Chimica Acta, vol. 413, no. 23-24, pp. 1861–1865, 2012. View at Google Scholar