The Establishment of Metabolic Syndrome Model by Induction of Fructose Drinking Water in Male Wistar Rats

Table 2

Effects of fructose drinking water on metabolic variables in C, F20, and F25 groups for 8 weeks.

Variables	C		F20		F25
	Baseline	8 weeks	Baseline	8 weeks	Baseline	8 weeks
Body weight gain (%)	—	36.12±0.81	—	43.03±0.76^ab	—	39.75±0.33^ad
Body mass index (g/cm²)	0.64±0.01	0.66±0.02	0.64±0.02	0.91±0.02^abc	0.66±0.01	0.77±0.01^abd
Abdominal circumference (cm)	16.5±0.26	18.3±0.1	16.1±0.40	22.9±0.3^abc	16.5±0.32	21.1±0.4^abd
Total abdominal fat (mg/mm tibial length)	—	196.72±23.13	—	437.97±27.08^ac	—	347.48±22.66^ad
Plasma triglyceride (mmol/L)	0.70±0.09	0.65±0.08	0.78±0.07	1.22±0.14^ab	0.70±0.08	1.13±0.09^ab
Plasma total cholesterol (mmol/L)	1.5±0.01	1.6±0.1	1.5±0.04	1.5±0.1	1.5±0.11	1.5±0.1
Systolic blood pressure (mmHg)	103.3±1.1	105.0±1.8	101.3±2.1	145.8±1.5^ab	104.5±1.1	142.5±1.1^ab
Plasma glucose (mmol/L)	5.1±0.4	6.4±0.2	4.7±0.4	8.1±0.6^ab	4.8±0.5	8.4±0.9^ab

Values are mean ± SEM and  𝑛=6 for each group. Superscript letters are significantly different. aA significant difference as compared to C group at 8 weeks. bA significant difference within group as compared to baseline. cA significant difference as compared to F25 group at 8 weeks. dA significant difference as compared to F20 group at 8 weeks.