Interactions of Neuropathogenic Escherichia coli K1 (RS218) and Its Derivatives Lacking Genomic Islands with Phagocytic Acanthamoeba castellanii and Nonphagocytic Brain Endothelial Cells

Figure 1

Comparative genomes of E. coli K1 and E. coli K-12. Common DNA: large circle represents the common E. coli backbone. K1-specific elements: 22 (numbered) islands of K1-specific DNA are represented as smaller circles and a plasmid. K-12-specific elements: 20 kb K-12 specific DNA is indicated in grey (referred to as a “black hole” in K1 genome). Adopted from Xie et al. [12].