Effects of Converting Tacrolimus Formulation from Twice-Daily to Once-Daily in Liver Transplantation Recipients
Figure 3
The serum levels of creatinine and uric acid before and after formulation conversion. (a) The median (interquartile) level of creatinine was decreased from 1.050 (0.870–1.330) mg/mL to 1.015 (0.820–1.310) mg/mL at 1 month (), 1.020 (0.820–1.310) mg/mL at 3 months (), and 1.030 (0.810–1.300) mg/mL at 6 months (). It increased to 1.080 (0.835–1.315) mg/mL again at 9 months (). (b) The median (interquartile) level of uric acid was decreased from 6.75 (5.70–7.70) mg/mL to 6.40 (5.40–7.40) at 1 month (), 6.40 (5.15–7.45) mg/mL at 3 months (), and 6.30 (5.30–7.50) mg/mL at 6 months (). It increased to 6.50 (5.60–7.70) mg/mL again at 9 months ().
