Research Article

Relating Education, Brain Structure, and Cognition: The Role of Cardiovascular Disease Risk Factors

Figure 1

(a) Theoretical model testing: (1) the association between education and regional grey and white matter volumes (Aim i); (2) the mediating effects of regional grey/white matter volumes on the association between education and cognition (Aim ii); and (3) the mediating effects of number of cardiovascular disease risk factors on the association between education and regional grey/white matter volumes (Aim iii). (b) Significant bias corrected standardised regression weights from a bootstrap of 1000 samples. The final model depicts the significant associations between education, cardiovascular disease risk factors, regional brain volumes, and cognitive test performance.
271487.fig.001a
(a) Theoretical model
271487.fig.001b
(b) Final model