Relating Education, Brain Structure, and Cognition: The Role of Cardiovascular Disease Risk Factors
Figure 1
(a) Theoretical model testing: (1) the association between education and regional grey and white matter volumes (Aim i); (2) the mediating effects of regional grey/white matter volumes on the association between education and cognition (Aim ii); and (3) the mediating effects of number of cardiovascular disease risk factors on the association between education and regional grey/white matter volumes (Aim iii). (b) Significant bias corrected standardised regression weights from a bootstrap of 1000 samples. The final model depicts the significant associations between education, cardiovascular disease risk factors, regional brain volumes, and cognitive test performance.