Research Article

Relating Education, Brain Structure, and Cognition: The Role of Cardiovascular Disease Risk Factors

Table 4

Unstandardised biased corrected effects with 95% CI and significance level from a bootstrap of 1000 samples.

CVD risk factorsGrey matter volumesWhite matter volumesIRSDMTCOWAT-ASTW
(95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI) (95% CI)

Reduced model
 Education−0.085  
(−0.174–0.009)
0.204**   
(0.100–0.297)
0.176***   
(0.108–0.247)
0.555*   
(0.113–1.032)
0.571***   
(0.272–0.964)
 CVRF−0.143*   
(−0.291–−0.001)
 Grey matter volumes0.268   
(−0.051–0.595)
2.542**   
(1.065–4.218)
 White matter volumes

CVD risk factors: cardiovascular disease risk factors, IR: immediate recall, SDMT: Symbol-Digit Modalities Test, COWAT-A: Controlled Oral Word Association Test for A-words, STW: Spot the Word, and CI: confidence interval.
; ; —: no effect to report.