Research Article
Designing Peptide-Based HIV Vaccine for Chinese
Table 3
Using novel algorism to calculate the coverage of epitopes in a published T helper vaccine for Chinese population.
| | Amino acid sequence | Protein destination1 | HIV%2 | DR%3 | Specific coverage4 |
| | FRKYTAFTIPSINNE | Pol 303 | 14% | 98% | 13% | | EKVYLAWVPAHKGIG | Pol 711 | 3% | 98% | 3% | | GEIYKRWIILGLNKI | Gag 294 | 20% | 87% | 18% | | KRWIILGLNKIVRMY | Gag 298 | 43% | 89% | 41% | | GAVVIQDNSDIKVVP | Pol 989 | 21% | 57% | 12% | | YRKILRQRKIDRLID | Vpu 31 | 2% | 89% | 2% | | QKQITKIQNFRVYYR | Pol 956 | 19% | 98% | 19% | | SPAIFQSSMTKILEP | Pol 335 | 11% | 93% | 11% | | QHLLQLTVWGIKQLQ | Env 729 | 23% | 83% | 21% | | AETFYVDGAANRETK | Pol 619 | 7% | 41% | 2% | | QGQMVHQAISPRTLN | Gag 171 | 3% | 85% | 3% | | WAGIKQEFGIPYNPQ | Pol 874 | 3% | 35% | 1% | | KVYLAWVPAHKGIGG | Pol 712 | 3% | 93% | 2% | | KTAVQMAVFIHNFKR | Pol 915 | 24% | 83% | 22% | | EVNIVTDSQYALGII | Pol 674 | 24% | 57% | 16% | | WEFVNTPPLVKLWYQ | Pol 596 | 22% | 91% | 22% | | HSNWRAMASDFNLPP | Pol 758 | 11% | 57% | 7% |
| | Total specific coverage5 | | | | 69% |
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The epitopes were selected from a published paper.
Data in columns 2–5 were calculated using the same method as in Table 2.
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