Research Article
Assessment of the Optic Disc Morphology Using Spectral-Domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy
Table 5
Best sensitivity-specificity balance of Cirrus OCT and HRT3 to discriminate between normal and glaucomatous eyes.
| | Optimal cut-off point | Sensitivity () | Sensitivity 95 CI | Specificity () | Specificity 95 CI | Sensitivity at fixed specificity | | Specificity 85 | Specificity 95 |
| | Cirrus OCT | | | | | | | | | Rim area | ≤1.2 | 98.1 | 90.1–100 | 86.3 | 76.2–96.2 | 96.1 | 80.7 | | Average C/D | >0.67 | 83.3 | 70.7–92.1 | 98.9 | 92.6–100 | 85.2 | 84.6 | | Vertical C/D | >0.59 | 94.2 | 84.6–98.8 | 93.4 | 84.7–97.7 | 77.5 | 86.5 | | Cup volume | >0.263 | 87.1 | 75.1–94.6 | 89.0 | 79.5–95.1 | 91 | 72.4 | | HRT3 | | | | | | | | | Rim area | ≤1.16 | 79.4 | 66.5–89.4 | 90.1 | 81.2–96.1 | 83.3 | 68.5 | | Average C/D | >0.39 | 86.5 | 74.7–94.5 | 94.5 | 86.6–98.5 | 90.3 | 80.7 | | Vertical C/D | >0.55 | 90.3 | 79.7–96.9 | 94.5 | 86.6–98.5 | 96.1 | 91 | | Cup volume | >0.14 | 83.3 | 70.7–92.1 | 86.3 | 76.2–93.2 | 81.4 | 59.6 |
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C/D: cup-to-disc ratio; CI: confidence interval.
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