CD49b, a Major Marker of Regulatory T-Cells Type 1, Predicts the Response to Antiviral Therapy of Recurrent Hepatitis C after Liver Transplantation
Figure 2
Relative expression of the CD49b marker using RT-PCR in responder and nonresponder groups. The responder group was defined by undetectable HCV RNA in peripheral blood, 18 and 30 months after beginning of the treatment (6 months after end of pegylated interferon + Ribavirin). (a) RT-PCR results obtained with Abi prism on sera from the patients. (b) RT-PCR results obtained with the light cycler in order to confirm Abi prism results on patient sera. (c) Results of RT-PCR on PBMC. (d) Results of RT-PCR on graft biopsies. Data are expressed as box plots in which the horizontal lines indicate the 25th, 50th, and 75th percentiles of the frequencies of the relative expression of CD49b, as measured by RT-PCR. The vertical lines represent the 10th and 90th percentiles.
