In Vitro Antioxidant, Antiproliferative, and Phytochemical Study in Different Extracts of Nyctanthes arbortristis Flowers

Table 2

Percentage inhibition of cancer cell proliferation and IC₅₀ values.

Sample	Cell type
	Colo 205		Y79		K562		MCF		MDA-MB
	% inhibition	IC50	% inhibition	IC50	% inhibition	IC50	% inhibition	IC50	% inhibition	IC50
NafE; (200 𝜇g/mL)	72.01±9.40	24.56±6.63^∗∗∗	81.82±2.11	55.87±7.19^∗∗	61.82±9.60	53.63±6.84^∗∗	54.24±5.39	184.36±5.39^∗	67.80±0.96	50.97±3.10^∗∗
NafEEa; (200 𝜇g/mL)	70.67±5.30	25.79±2.69^∗∗∗	68.06±2.02	59.50±3.41^∗∗	58.48±5.20	98.02±7.47^∗	46.57±0.64	214.73±0.64^∗	52.65±2.02	100.81±0.50^∗
Doxorubicin; (10 𝜇g/mL)	92.33±0.45	0.39±0.03	89.42±2.02	0.32±0.10	89.42±2.02	0.36±0.02	92.33±0.45	0.36±0.09	90.65±2.41	0.45±0.11
DMSO 2%; (Solvent Cntl)	3.71±0.56	—	3.73±1.53	—	3.76±1.00	—	4.44±1.70	—	4.02±1.17	—

Values were the means of four replicates ± standard deviation (SD). Significant 𝑃 values (^∗∗∗𝑃<0.001, ^∗∗𝑃<0.01, and ^∗𝑃<0.05) were obtained by Student’s 𝑡-test analysis. Composite treatments were compared using one-way analysis of variances (ANOVA) and probability values were found to be equal to or less than 0.05 for all the four cell lines.