The Influence of BMX Gene Polymorphisms on Clinical Symptoms after Mild Traumatic Brain Injury
Table 4
(a) Difference in BDI score among mTBI patients stratified by different BMX genotypes (first week). (b) Difference in BDI score among mTBI patients stratified by different BMX genotypes (sixth week).
(a)
SNP
Genotype
Number
Grade 1 (0–9)
Grade 2 (10–18)
Grade 3 (19–29)
Grade 4 (30–63)
aOR (95% CI) P value
bFisher’s exact test P value
rs35697037
AA + AG
107
66 (61.7)
30 (28.0)
8 (7.5)
3 (2.8)
0.81
GG
81
53 (65.4)
18 (22.2)
8 (9.9)
2 (2.5)
(0.33–2.0)
0.6562
—
rs16979956
TT + CT
3
3 (100.0)
0 (0.0)
0 (0.0)
0 (0.0)
0
CC
185
116 (62.7)
48 (26.0)
16 (8.6)
5 (2.7)
—
0.5358
1.0000
rs1877752
TT + CT
9
7 (77.8)
1 (11.1)
1 (11.1)
0 (0.0)
0.99
CC
179
112 (62.6)
47 (26.2)
15 (8.4)
5 (2.8)
(0.12–8.36)
0.9954
1.0000
rs16997078
GG + AG
7
5 (71.4)
1 (14.3)
1 (14.3)
0 (0.0)
1.34
AA
181
114 (63.0)
47 (26.0)
15 (8.3)
5 (2.8)
(0.15–11.72)
0.7897
0.5698
Grade 1 + Grade 2 versus Grade 3 + Grade 4. 20% of cells has expected count less than 5, Fisher’s exact test would be performed.
(b)
SNP
Genotype
Number
Grade 1 (0–9)
Grade 2 (10–18)
Grade 3 (19–29)
Grade 4 (30–63)
aOR (95% CI) P value
bFisher’s exact test P value
rs35697037
AA+ AG
64
42 (65.6)
13 (20.3)
7 (11.0)
2 (3.1)
1.96
GG
39
29 (74.4)
7 (17.9)
3 (7.7)
0 (0.0)
(0.50–7.75)
0.3284
0.5280
rs16979956
TT+CT
1
0 (0.0)
1 (100.0)
0 (0.0)
0 (0.0)
0
CC
102
71 (69.6)
19 (18.6)
10 (9.8)
2 (2.0)
—
0.7152
1.0000
rs1877752
TT+CT
4
2 (50.0)
1 (25.0)
1 (25.0)
0 (0.0)
2.67
CC
99
69 (69.7)
19 (19.2)
9 (9.1)
2 (2.0)
(0.25–27.92)
0.3960
0.3955
rs16997078
GG + AG
4
3 (75.0)
0 (0.0)
1 (25.0)
0 (0.0)
2.67
AA
99
68 (68.7)
20 (20.2)
9 (9.1)
2 (2.0)
(0.25–27.92)
0.3960
0.3955
Grade 1 + Grade 2 versus Grade 3 + Grade 4. b20% of cells has expected count less than 5, Fisher’s exact test would be performed.
