BioMed Research International / 2014 / Article / Tab 1 / Review Article
Therapeutically Targeting Neuroinflammation and Microglia after Acute Ischemic Stroke Table 1 Markers for distinguishing activated and resting microglia.
Name Markers References CD11b Both resting and activated M/M [24 , 75 ] CD45 Nucleated hematopoietic cell surface [30 , 76 ] CD68 (ED1)* Active phagocytosis M/M [24 , 45 , 77 ] Iba-1 Both resting and activated M/M [78 , 79 ] F4/80 Both resting and activated M/M [35 , 43 ] IB4 Both resting and activated M/M [15 ] Ym-1 Activated M/M (M2) [24 ] Iba-1+ , CD206+ Activated M/M (M2) [24 ] Iba-1+ , CD16/32+ Activated M/M (M1) [41 ]
CD68 and ED1 are virtually the same molecule (CD68 is used more in the human context, while ED1 is the name of that protein in rodents). M/M: microglia and macrophages.