Therapeutically Targeting Neuroinflammation and Microglia after Acute Ischemic Stroke

Table 2

Microglial marker expressions in the ischemic core and peri-infarct zone.

Location	Marker	Model	Expression; (after reperfusion)	Reference
Ischemic core	Iba1	1.5 h tMCAO	24 h, 4–7 d (peak)	[45]
	Iba1^+, ED1^+	1.5 h tMCAO	7 d	[45]
	CD11b	1 h tMCAO	24 h	[23]
	CD68	pMCAO	7 d	[24]
	Ym-1	pMCAO	24 h
	CD206	pMCAO	24 h
	Iba1^+, CD206^+	1 h tMCAO	1 d, 5 d (peak)	[41]
	Iba1^+, CD16/32^+	1 h tMCAO	3 d, 14 d (peak)
Peri-infarct zone	Iba1^+, ED1^−	1.5 h tMCAO	3.5 h, 7 d (peak)	[45]
	CD11b^+, CD68^+	pMCAO	6 h	[24]
	F4/80	pMCAO	24 h, 3 d (peak)	[49]
	CD11b	pMCAO	1 h	[23]
	CD68	pMCAO	24 h	[24]
	CD68^+, MHC II^+	pMCAO	3–7 d	[51]

pMCAO: permanent middle cerebral artery occlusion and tMCAO: transient middle cerebral artery occlusion.