Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 297808, 8 pages
http://dx.doi.org/10.1155/2014/297808
Research Article

Comparing Microspheres with Different Internal Phase of Polyelectrolyte as Local Drug Delivery System for Bone Tuberculosis Therapy

1School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
2National Engineering Center for Tissue Restoration and Reconstruction, Guangzhou 510006, China
3Department of Materials Science and Engineering, Jinan University, Guangzhou 510632, China

Received 7 November 2013; Revised 31 December 2013; Accepted 12 January 2014; Published 23 February 2014

Academic Editor: Jiang Chang

Copyright © 2014 Gang Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. I. Grosskopf, A. B. David, G. Charach, I. Hochman, and S. Pitlik, “Bone and joint tuberculosis—a 10-year review,” Israel Journal of Medical Sciences, vol. 30, no. 4, pp. 278–283, 1994. View at Google Scholar · View at Scopus
  2. M. Martini and M. Ouahes, “Bone and joint tuberculosis: a review of 652 cases,” Orthopedics, vol. 11, no. 6, pp. 861–866, 1988. View at Google Scholar · View at Scopus
  3. P. C. Jutte and J. H. Van Loenhout-Rooyackers, “Routine surgery in addition to chemotherapy for treating spinal tuberculosis,” Cochrane Database of Systematic Reviews, no. 1, Article ID CD004532, 2006. View at Google Scholar · View at Scopus
  4. E. E. Vogelpoel, J. J. Been, and A. A. de Gast, “Two-stage treatment of acetabular bone defect in tuberculosis of the hip by intended ankylosis followed by total hip arthroplasty: a case report,” Cases Journal, vol. 2, article 6532, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Ramachandran, I. J. Clifton, T. A. Collyns, J. P. Watson, and S. B. Pearson, “The treatment of spinal tuberculosis: a retrospective study,” International Journal of Tuberculosis and Lung Disease, vol. 9, no. 5, pp. 541–544, 2005. View at Google Scholar · View at Scopus
  6. W. Wu, Q. Zheng, X. Guo, and W. Huang, “The controlled-releasing drug implant based on the three dimensional printing technology: fabrication and properties of,” Journal Wuhan University of Technology, Materials Science Edition, vol. 24, no. 6, pp. 977–981, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. W. Wu, Q. Zheng, X. Guo, J. Sun, and Y. Liu, “A programmed release multi-drug implant fabricated by three-dimensional printing technology for bone tuberculosis therapy,” Biomedical Materials, vol. 4, no. 6, Article ID 065005, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. D. H. R. Kempen, L. Lu, A. Heijink et al., “Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration,” Biomaterials, vol. 30, no. 14, pp. 2816–2825, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. T. N. Vo, F. K. Kasper, and A. G. Mikos, “Strategies for controlled delivery of growth factors and cells for bone regeneration,” Advanced Drug Delivery Reviews, vol. 64, no. 12, pp. 1292–1309, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. X. Wang, E. Wenk, X. Zhang, L. Meinel, G. Vunjak-Novakovic, and D. L. Kaplan, “Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering,” Journal of Controlled Release, vol. 134, no. 2, pp. 81–90, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Lee, W. Li, R. K. Siu et al., “Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers,” Biomaterials, vol. 30, no. 30, pp. 6094–6101, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Zhao, M. Shinkai, T. Takezawa, S. Ohba, U. I. Chung, and T. Nagamune, “Bone regeneration using collagen type I vitrigel with bone morphogenetic protein-2,” Journal of Bioscience and Bioengineering, vol. 107, no. 3, pp. 318–323, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. S. S. Kim, S. J. Gwak, and B. S. Kim, “Orthotopic bone formation by implantation of apatite-coated poly(lactide-co-glycolide)/hydroxyapatite composite particulates and bone morphogenetic protein-2,” Journal of Biomedical Materials Research A, vol. 87, no. 1, pp. 245–253, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. G. B. Migliori, R. Centis, C. Lange, M. D. Richardson, and G. Sotgiu, “Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia: current status and global perspectives,” Current Opinion in Pulmonary Medicine, vol. 16, no. 3, pp. 171–179, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Ködmön, V. Hollo, E. Huitric, A. Amato-Gauci, and D. Manissero, “Multidrug- and extensively drug-resistant tuberculosis: a persistent problem in the European union European union and European economic area,” Euro Surveillance, vol. 15, no. 11, article 2, 2010. View at Google Scholar · View at Scopus
  16. S. E. Berning, “The role of fluoroquinolones in tuberculosis today,” Drugs, vol. 61, no. 1, pp. 9–18, 2001. View at Google Scholar · View at Scopus
  17. S. Saigal, S. R. Agarwal, H. P. Nandeesh, and S. K. Sarin, “Safety of an ofloxacin-based antitubercular regimen for the treatment of tuberculosis in patients with underlying chronic liver disease: a preliminary report,” Journal of Gastroenterology and Hepatology, vol. 16, no. 9, pp. 1028–1032, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. S. M. Hwang, D. D. Kim, S. J. Chung, and C. K. Shim, “Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis,” Journal of Controlled Release, vol. 129, no. 2, pp. 100–106, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Harsha, R. Chandramouli, and S. Rani, “Ofloxacin targeting to lungs by way of microspheres,” International Journal of Pharmaceutics, vol. 380, no. 1-2, pp. 127–132, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Nasr, G. A. S. Awad, S. Mansour, I. Taha, A. A. Shamy, and N. D. Mortada, “Different modalities of NaCl osmogen in biodegradable microspheres for bone deposition of risedronate sodium by alveolar targeting,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 79, no. 3, pp. 601–611, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. M. J. Heslinga, E. M. Mastria, and O. Eniola-Adefeso, “Fabrication of biodegradable spheroidal microparticles for drug delivery applications,” Journal of Controlled Release, vol. 138, no. 3, pp. 235–242, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. V. Tran, J. Benoît, and M. Venier-Julienne, “Why and how to prepare biodegradable, monodispersed, polymeric microparticles in the field of pharmacy?” International Journal of Pharmaceutics, vol. 407, no. 1-2, pp. 1–11, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Barzegar-Jalali, M. Alaei-Beirami, Y. Javadzadeh et al., “Comparison of physicochemical characteristics and drug release of diclofenac sodium-eudragit RS100 nanoparticles and solid dispersions,” Powder Technology, vol. 219, pp. 211–216, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. X. Song, Y. Zhao, W. Wu et al., “PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: systematic study of particle size and drug entrapment efficiency,” International Journal of Pharmaceutics, vol. 350, no. 1-2, pp. 320–329, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Peltonen, J. Aitta, S. Hyvönen, M. Karjalainen, and J. Hirvonen, “Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l)lactide nanoparticles,” AAPS PharmSciTech, vol. 5, no. 1, article E16, 2004. View at Google Scholar · View at Scopus
  26. W. S. Cheow and K. Hadinoto, “Enhancing encapsulation efficiency of highly water-soluble antibiotic in poly(lactic-co-glycolic acid) nanoparticles: modifications of standard nanoparticle preparation methods,” Colloids and Surfaces A, vol. 370, no. 1-3, pp. 79–86, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Ayoub, N. Ahmed, N. Kalaji et al., “Study of the effect of formulation parameters/variables to control the nanoencapsulation of hydrophilic drug via double emulsion technique,” Journal of Biomedical Nanotechnology, vol. 7, no. 2, pp. 255–262, 2011. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Mao, Y. Shi, L. Li, J. Xu, A. Schaper, and T. Kissel, “Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 68, no. 2, pp. 214–223, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. Z. Wang, “Effects of the process parameters on the initial burst release of poly(lactide-co-glycolide) microspheres containing bovine serum albumin by the double-emulsion solvent evaporation/extraction method,” Journal of Applied Polymer Science, vol. 115, no. 5, pp. 2599–2608, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. A. S. Ginsburg, J. H. Grosset, and W. R. Bishai, “Fluoroquinolones, tuberculosis, and resistance,” The Lancet Infectious Diseases, vol. 3, no. 7, pp. 432–442, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. Y. Y. Yang, T. S. Chung, X. L. Bai, and W. K. Chan, “Effect of preparation conditions on morphology and release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion method,” Chemical Engineering Science, vol. 55, no. 12, pp. 2223–2236, 2000. View at Publisher · View at Google Scholar · View at Scopus
  32. N. Nihant, C. Schugens, C. Grandfils, R. Jerome, and P. Teyssie, “Polylactide microparticles prepared by double emulsion/evaporation technique. I. Effect of primary emulsion stability,” Pharmaceutical Research, vol. 11, no. 10, pp. 1479–1484, 1994. View at Publisher · View at Google Scholar · View at Scopus