The Role of Vitamin D Deficiency and Vitamin D Receptor Genotypes on the Degree of Collateralization in Patients with Suspected Coronary Artery Disease

Table 1

Demographic and laboratory characteristics of the patients with different severity of coronary artery disease.

	Severity of CAD¶
	Class 0 (𝑁=118)	Class 1 (𝑁=202)	Class 2 (𝑁=168)	Class 3 (𝑁=272)	Total; (𝑁=760)	𝑃 value
Male % (𝑁)	57.60 (68)	70.30 (142)	86.90 (146)	83.10 (226)	76.60 (582)	0.01
Age (year)*	57.46±10	55.96±12.48	58.42±9.80	59.41±9.49	57.97±10.58	0.005
History of smoking % (𝑁)	17.79 (21)	59.90 (121)	57.14 (96)	62.86 (171)	53.81 (409)	0.001
BMI > 30 kg/m^2	18.64 (22)	22.70 (46)	26.19 (44)	26.10 (71)	24.07 (183)	0.01
HTN (140/90)	42.37 (50)	54.45 (110)	48.80 (82)	52.94 (144)	50.78 (386)	0.17
FBS > 110 mg/dL	6.80 (8)	13.90 (28)	13.10 (22)	15.10 (41)	13.0 (99)	0.15
TG > 150 mg/dL	14.40 (17)	33.66 (68)	34.52 (58)	42.27 (115)	33.94 (258)	0.01
LDL > 160 mg/dL	3.38 (4)	7.42 (15)	6.54 (11)	8.82 (24)	7.10 (54)	0.2
HDL < 35 mg/dL	3.38 (4)	20.29 (41)	27.38 (46)	28.67 (78)	22.23 (169)	0.001
Total cholesterol > 200 mg/dL	18.64 (22)	22.77 (46)	26.19 (44)	26.83 (73)	24.34 (185)	0.29
Severe vitamin D deficiency < 10 ng/mL	56.77 (67)	61.88 (125)	74.40 (125)	78.30 (213)	69.73 (530)	0.001
Vitamin D levels (ng/mL)*	8.17±5.06	8.03±5.35	7.68±5.83	5.77±5.24	7.19±5.24	0.001
FF genotype	64.4 (76)	51.5 (104)	48.8 (82)	55.9 (152)	54.47 (414)	0.05
ff genotype	6.8 (8)	7.9 (16)	7.1 (12)	8.1 (22)	7.63 (58)	0.9
Ff genotype	28.8 (34)	40.6 (82)	44.0 (74)	36.0 (98)	37.89 (288)	0.04
Left ventricular ejection fraction*	49.45±8.49	49.47±10.23	49.35±9.05	45.08±9.26	47.77±9.59	0.001

∗Mean ± standard deviation.
¶CAD: coronary artery disease, BMI: body mass index, FBS: fasting blood sugar, FokI VDR genotypes: FF, ff, Ff, HTN: hypertension, HDL: high-density lipoprotein, LDL: low-density lipoprotein, and TG: triglyceride.